Fluorescence-navigated Thoracoscopy for Pulmonary Segmentectomy
Not Applicable
- Conditions
- Pulmonary Segmentectomy
- Interventions
- Procedure: Indocyanine Green Injection through Peripheral Vein
- Registration Number
- NCT04160884
- Lead Sponsor
- Peking University People's Hospital
- Brief Summary
Recently developed fluorescence-navigated thoracoscopy with indocyanine green (ICG) is being used for various kinds of pulmonary surgery, and several studies have reported the application of this novel technique in demarcation of the intersegmental border for segmentectomy. This study is performed prospectively to find out, for the first time, the optimal dosage of ICG in human body to ensure safe and sustained imaging during segmentectomy.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- All
- Target Recruitment
- 68
Inclusion Criteria
- Suitable for segmentectomy and signed informed consent
Exclusion Criteria
- Liver dysfunction.
- Allergic to indocyanine green.
- Can't tolerate thoracoscopic surgery.
Study & Design
- Study Type
- INTERVENTIONAL
- Study Design
- PARALLEL
- Arm && Interventions
Group Intervention Description B Indocyanine Green Injection through Peripheral Vein 0.2mg/kg of ICG, iv A Indocyanine Green Injection through Peripheral Vein 0.6mg/kg of ICG, iv
- Primary Outcome Measures
Name Time Method Signal-to-background Ratio (SBR) of the Targeted and Non-targeted Segments Surgery We use image analysis software ImageJ to evaluate the strength of luminosity in the targeted and non-target segments using intraoperative images and calculate signal-to-background-ratio.
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (1)
Peking University People's Hospital
🇨🇳Beijing, Beijing, China