ISRCTN97157037
Completed
Phase 4
A randomized controlled trial evaluating the effects of Diosmin in the treatment of radicular pain caused by lumbar intervertebral disc protrusion
anjing Drum Tower Hospital0 sites300 target enrollmentJune 13, 2017
Overview
- Phase
- Phase 4
- Intervention
- Not specified
- Conditions
- Radicular pain
- Sponsor
- anjing Drum Tower Hospital
- Enrollment
- 300
- Status
- Completed
- Last Updated
- 7 years ago
Overview
Brief Summary
2017 results in https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5651095/
Investigators
Eligibility Criteria
Inclusion Criteria
- •1\. Preliminarily diagnosis of radicular pain
- •2\. Aged 18 years and over
- •3\. Pain duration at least 30 days
- •4\. Underwent routine discography
- •5\. Previously treated with nonsteroidal anti\-inflammatory drugs, opioid medications or physical therapy without pain relief for more than one month
- •6\. Normal or slight decrease in the height of disc space on lateral plain X\-ray film
- •7\. Initially considered eligible for surgical intervention
Exclusion Criteria
- •1\. Spondylolysis
- •2\. Lumbar canal stenosis
- •3\. Isthmic or degenerative spondylolisthesis
- •4\. Inflammatory arthritis
- •5\. Spinal instability
- •6\. Infection from previous lumbar surgery
- •7\. Neurologic disease
- •9\. Psychological disorders (such as depression or using antidepressant/anxiolytic medications)
Outcomes
Primary Outcomes
Not specified
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