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Clinical Trials/NCT00243360
NCT00243360
Completed
Not Applicable

Optimizing Antibiotic Use in Long Term Care

Agency for Healthcare Research and Quality (AHRQ)1 site in 1 countryJanuary 2001
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ConditionsUrinary Tract Infection, Antibiotic Use

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Urinary Tract Infection, Antibiotic Use
Sponsor
Agency for Healthcare Research and Quality (AHRQ)
Locations
1
Primary Endpoint
Antimicrobial prescriptions
Status
Completed
Last Updated
20 years ago
OverviewInvestigatorsEligibility CriteriaOutcomesSitesSimilar Trials

Overview

Brief Summary

The purpose of this study was to determine if a multi-faceted intervention to implement diagnostic and therapeutic algorithms for management of suspected urinary infection in nursing home residents could reduce antibiotic prescribing for urinary indications in this population.

Detailed Description

Antibiotic use is intense in nursing homes and frequently inappropriate when prescribed for urinary indications. Evidence from randomized controlled trials suggests that treatment of asymptomatic bacteriuria, the presence of bacteria in the urine in the absence of urinary symptoms, is not beneficial. Despite this, one in three prescriptions for urinary indications are for asymptomatic bacteriuria. To improve antibiotic prescribing in this setting we conducted a cluster randomized trial of a strategy to implement diagnostic and treatment algorithms for urinary infection. 24 nursing homes were randomized to either the intervention (implemented at the nursing home level using a multi-faceted approach: small group interactive sessions for nurses, one-on-one interviews for physicians, videotapes, written material, and outreach visits) or to usual care.

Registry
clinicaltrials.gov
Start Date
January 2001
End Date
July 2003
Last Updated
20 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Agency for Healthcare Research and Quality (AHRQ)

Eligibility Criteria

Inclusion Criteria

  • •Individuals- all residents eligible
  • •Nursing homes
  • •Free standing long term care facilities with \>100 beds
  • •No stated policy for diagnosis or treatment of urinary tract infections
  • •The facility agrees to refrain from introducing new strategies for antibiotic utilization or clinical pathways during study

Exclusion Criteria

  • Not provided

Outcomes

Primary Outcomes

Antimicrobial prescriptions

Secondary Outcomes

  • Urinary cultures,
  • hospitalizations, deaths

Study Sites (1)

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