Multi-omics Study of Early-stage Lung Cancer with Distinct Phenotypes
- Conditions
- Lung Cancer Associated with Cystic AirspacesMultiple Primary Lung CancersNon-Small Cell Lung Cancer
- Registration Number
- NCT06699979
- Brief Summary
The goal of this observational study is to investigate the multi-omics characterization early-stage lung cancer exhibiting distinct phenotypes including lung cancer associated with cystic airspaces, multiple primary lung cancers, and so on. The main questions it aims to answer are:
* What are the differences in pathogenesis of non-small cell lung cancer with different phenotypes explored by multi-omics?
* Whether differential genes lead to potential prognostic models and therapeutic targets? Participants will be followed up after surgery to answer prognosis: whether they have recurred, and the time to recurrence.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- RECRUITING
- Sex
- All
- Target Recruitment
- 300
Not provided
Not provided
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Immune repertoire sequencing From enrollment to the end of surgery for 3 years DNA methylome sequencing From enrollment to the end of surgery for 3 years RNA sequencing From enrollment to the end of surgery for 3 years
- Secondary Outcome Measures
Name Time Method Metabolomics analysis From enrollment to the end of surgery for 3 years Radiomics analysis From enrollment to the end of surgery for 3 years Genomic sequencing From enrollment to the end of surgery for 3 years
Related Research Topics
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Trial Locations
- Locations (1)
The Second Xiangya Hospital of Central South University
🇨🇳Changsha, Hunan, China