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临床试验/NCT00604149
NCT00604149已完成不适用

Etude Multicentrique en Population de la susceptibilité génétique à Faire Une Mort Subite

Institut National de la Santé Et de la Recherche Médicale, France1 个研究点 分布在 1 个国家目标入组 2,332 人开始时间: 2008年1月1日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
2,332
试验地点
1
主要终点
Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome

研究概览

简要总结

Sudden death is a major problem in industrially developed countries. Despite a decline in ischemic heart disease mortality and the progress has been made in resuscitation, treatment of sudden death victims is frequently unsuccessful. the ideal solution would be to prevent the disease process that causes the initial episode of cardiac arrest. Parental sudden death is an independent risk factor for sudden death. So, detect a gene predisposing to sudden death may help provide better identification of subjects at high risk of cardiac arrest. This research is a genetic study of sudden cardiac death, recruited 2000 subjects in out-of-hospital cardiac arrest.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Prospective

入排标准

年龄范围
18 Years 至 75 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Aged from 18 to 75 years

排除标准

  • People not free
  • Inhospital subjects
  • Death by other disease
  • Violent death

研究组 & 干预措施

1

case of out-of-hospital cardiac arrest

2

cases of MI

3

controls without coronary disease

结局指标

主要结局

Frequency of Single Nucleotide Polymorphism (SNP) across the entire genome

时间窗: Day 1

DNA extracted from blood cells

次要结局

未报告次要终点

研究者

发起方
Institut National de la Santé Et de la Recherche Médicale, France
申办方类型
Other Gov
责任方
Sponsor

研究点 (1)

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