Photodynamic Lasertherapy (PDT) in Periodontal Treatment (in Vivo)

Phase 2

Completed

• Conditions: Periodontal Disease

• Registration Number: NCT00196456
• Lead Sponsor: University Medicine Greifswald

Brief Summary

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal patients

Detailed Description

The purpose of the study is to evaluate the effect of the photodynamic therapy in periodontal pockets and to assess the reduction of subgingival bacteria.

The first step will include the evaluation of the quantity of the light which will activate the photosensitizer in the various niches in the periodontal pocket.

The second step will evaluate the distribution of the photosensitizer in the periodontal pocket.

The third step will assess the woundhealing of the the photodynamic therapy compared to conventional periodontal therapy with an ultrasonic device.

Study Timeline

• Study Start: 2004-04
• Study Completion: 2005-01
• Status Verified: 2005-09
• Study First Submitted: 2005-09-12
• Study First Submitted QC: 2005-09-12
• Last Update Submitted: 2005-09-12
• Study First Posted: 2005-09-20
• Last Update Posted: 2005-09-20

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• systemic healthy
• >15 teeth
• ≤ 6 mm >2 teeth
• age > 35 years

Exclusion Criteria

• • systemic ill
• cardiac pacemaker
• < 15 teeth

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
pocket depth reduction

Secondary Outcome Measures

Name	Time	Method
attachmentlevel loss

Trial Locations

Locations (1)

Ernst-Moritz-Arndt-Universität Greifswald; 🇩🇪 Greifswald, Mecklenburg-Vorpommern, Germany