Association between oral hypofunction and heart disease
Not Applicable
Recruiting
- Conditions
- heart disease
- Registration Number
- JPRN-jRCT1030230205
- Lead Sponsor
- Koba Shinji
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- Not specified
- Target Recruitment
- 300
Inclusion Criteria
Hospitalized patients due to heart disease who are 50 years of age or older, and are underwent cardiac rehabilitation
All patients provided written informed consent.
Exclusion Criteria
Patients unable to answer the questionnaire due to severe cognitive dysfunction
Patients who cannot have a dental examination because of difficulty sitting or limited mouth opening.
Investigator made the patient unsuitable for inclusion.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Investigation of oral hypofunction and physical performance, and effects of oral hypofunction on clinical outcomes of heart diseases
- Secondary Outcome Measures
Name Time Method Association between each component of oral hypofunction and cardiopulmonary capacity (cardiopulmonary exercise test or 6-min walking distance)<br>Comparison of blood biomarkers between presence and absence of oral hypofunction<br>Association between each component of oral hypofunction and physical performance such as short physical performance battery, skeletal muscle mass, knee extension strength, or grip strength<br>Association between each component of oral hypofunction and advanced glycation end products<br>Association between each component of oral hypofunction and dietary style or malnutrition<br>Association between each component of oral hypofunction and cognitive function<br>Association between each component of oral hypofunction and QOL evaluated by SF-12