ISRCTN22639386未知未知
Autologous bone marrow-derived cells for cardioprotection during heart surgery
niversity Hospitals of Leicester NHS Trust (UK)0 个研究点目标入组 44 人开始时间: 2007年2月14日最近更新:
适应症
试验速览
- 阶段
- 未知
- 发起方
- 入组人数
- 44
研究概览
简要总结
2004 Abstract results in http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=15040600 2006 Abstract results in http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=pubmed&cmd=Retrieve&dopt=AbstractPlus&list_uids=17059931 2009 Results article in https://pubmed.ncbi.nlm.nih.gov/19561024/ (added 19/07/2021)
研究设计
- 研究类型
- Interventional
入排标准
入选标准
- •1. Triple vessel coronary artery disease with or without significant disease of the left main stem with indication of elective surgical revascularisation
- •2. Left ventricular ejection fraction greater than 40%
- •3. Age 20 to 80 years
排除标准
- •In addition to not being compliant to the inclusion criteria, the following criteria will be sufficient to exclude patients from entering the study:
- •1. Cardiogenic shock (need for inotropic drugs, intra-aortic balloon pump)
- •2. Previous Coronary Artery Bypass Graft (CABG)
- •3. Percutaneous Coronary Infusion (PCI) in the previous three months
- •4. History of neoplastic disease
- •5. History of bleeding disorder
- •6. Chronic inflammatory disease
- •7. Active infection
- •8. Renal impairment (creatinine more than 180 mmol/l)
- •9. Liver dysfunction (Glutamate Oxalate Transferase [GOT] more than 2 x Upper Limit of Normal [ULN] or International Normalised Ratio [INR] more than 1.5 x ULN)
- •10. Diabetes
- •11. Chronic treatment with oral antibiotic agents
研究者
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