The Effect of Combined Supplementation of Berberine and Fenugreek Seed Powder on Inflammatory Factors and Lipid and Glucose Profile in Patients with Type 2 Diabetes

Phase 3

Recruiting

• Conditions: Diabetes mellitus due to underlying condition; Type 2 diabetes.

• Registration Number: IRCT20191229045937N1
• Lead Sponsor: Ahvaz University of Medical Sciences

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 24 February 2020

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 50

Inclusion Criteria

Having over 25BMI, at least 1 year of diabetes, 25-65 year olds with type 2 diabetes, taking blood sugar lowering diabetes medications, no pregnancy and lactation, no chronic diseases (liver, kidney, heart, thyroid, Rheumatic, Pulmonary, Metabolic, Digestive, Malignancies, Allergies), No insulin requirement, No use of dietary supplements, vitamins and minerals at least 3 months before study, No hormone therapy, No smoking, No use of other medicinal products Routine face at least 3 months before study, written informed consent from patients
at least 1 year of diabetes
25-65 year olds with type 2 diabetes
taking blood sugar lowering diabetes medications
no pregnancy and lactation
no chronic diseases (liver, kidney, heart, thyroid, Rheumatic, Pulmonary, Metabolic, Digestive, Malignancies, Allergies)
No insulin requirement
No use of dietary supplements, vitamins and minerals at least 3 months before study
No hormone therapy
No smoking
No use of other medicinal products Routine face at least 3 months before study
written informed consent from patients

Exclusion Criteria

Not willing to continue cooperation
Specific diseases (liver, kidney, heart, thyroid, rheumatic, pulmonary, metabolic, gastrointestinal, malignant, allergic) during study
pregnancy initiation and lactation
Start insulin treatment
Start taking supplements, vitamins and minerals
Changes in the dosage of oral hypoglycemic agents
Changes in the amount of physical activity during the study
Start taking other medicinal products routinely
Pregnant and lactating women
Past 6 months drug or alcohol use history
Taking steroidal anti-inflammatory drugs and fiber supplements
Weight loss diet at least 6 months before the intervention
Use of dietary supplements and other herbal remedies at least 3 months before intervention

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Inflammatory factors and lipid and sugar profiles. Timepoint: Evaluation of inflammatory factors and lipid profile and glucose profile at baseline and 12 weeks after starting supplementation with berberine and fenugreek. Method of measurement: Blood serum separation.