18F-FDG PET/CT versus CT imaging in staging of primary Muscle Invasive Bladder Cancer

Recruiting

• Conditions: bladder cancer; urothelial cell carcinoma; 10038364

• Registration Number: NL-OMON43864
• Lead Sponsor: eids Universitair Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 120

Inclusion Criteria

-All patients with a clinical diagnosis of muscle invasive bladder cancer with active disease identified within the bladder at the time of consent and imaging.
-Patients with primary resectable tumour in the bladder, clinically suspect of invasive bladder carcinoma, who are potential candidates for radical cystectomy plus lymphadenectomy, will be eligible with residual disease in the bladder at the time of imaging.
-All patients will have consented to diagnostic imaging procedures.

Exclusion Criteria

- Prior biopsy of the primary bladder tumour within 6 months before PET/CT imaging
- Prior BCG instillations.
- Treatment with bladder instillations other than with BCG less than 6 months ago
- Patients with sarcoidosis, tuberculosis and/or lymphatic disorders
* Prior pelvic radiation for bladder cancer
- Patients deemed not appropriate surgical candidates
- Patients that cannot tolerate being in the PET scanner or deemed unable to receive a contrast enhanced CT.
- Patients who are pregnant or lactating

Study & Design

• Study Type: Observational non invasive
• Study Design: Not specified