Prospective study of HBV reactivation in patients with chronic HCV infection, treated with direct acting antivirals
Not Applicable
- Conditions
- Chronic liver disease with HCV
- Registration Number
- JPRN-UMIN000024019
- Lead Sponsor
- Osaka City University
- Brief Summary
HBV reactivation occurred in 3 of 22 patients co-infected with HBV and HCV during anti-HCV therapy. On the other hand, in only one patient with resolved HBV infection, HBV DNA was detected during anti-HCV therapy, Hepatitis flare did not occur in patients with HBV reactivation.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete: follow-up complete
- Sex
- All
- Target Recruitment
- 790
Inclusion Criteria
Not provided
Exclusion Criteria
Negative for all of HBV serum markers; HBsAg, anti-HBc, anti-HBs. Patients who continue the other viral therapy. Patients cannot be checked regularly. Less than 15 years old. Doctor recognize a patient unsuitable to enroll the study.
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method