Titanium-prepared Platelet Rich Fibrin Versus Connective Tissue Graft for Management of Type-2 Gingival Recession

Not Applicable

Completed

• Conditions: Gingival Recession
• Interventions: Other: T-PRF with CAF; Other: SECTG with CAF

• Registration Number: NCT06621433
• Lead Sponsor: Rizk Beshir

Brief Summary

The aim of the study is to evaluate the effectiveness of using titanium prepared platelet rich fibrin with coronally advanced flap in the treatment of type-2 Cairo gingival recession.

Detailed Description

Not available

Study Timeline

• Study Start: 2023-01-01
• Primary Completion: 2024-01-20
• Study Completion: 2024-01-22
• Status Verified: 2024-09
• Study First Submitted: 2024-09-26
• Study First Submitted QC: 2024-09-28
• Last Update Submitted: 2024-09-28
• Study First Posted: 2024-10-01
• Last Update Posted: 2024-10-01

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 44

Inclusion Criteria

• Gingival recession type 2 according to Cairo et al (2011).
• Adequate amount of Attached Gingiva (AG) (2 mm≤ AG).
• Good oral hygiene (full mouth bleeding score and O'Leary index less than ≤10 % after complete phase I therapy)
• Clinically thick gingival biotype (1mm < gingival thickness).
• Anterior esthetic zone.

Exclusion Criteria

• Patients with gingival recession types 1 and 3 according to Cairo et al.
• Inadequate amount of attached gingiva (AG < 2 mm).
• Uncooperative patients.
• Smoking more than 10 cigarettes per day.
• Patients with known systemic conditions or taking medications that may affect soft tissue healing.
• Pregnant and lactating women.
• Patients with parafunctional habits.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
Coronally advanced flap (CAF) in conjunction with titanium prepared PRF	T-PRF with CAF	-
CAF in conjunction with subepithelial connective tissue graft (SECTG)	SECTG with CAF	-

Primary Outcome Measures

Name	Time	Method
Probing depth	up to 6 months	The distance from the base of the pocket to the most apical point on the gingival margin will be measured using a periodontal probe.
Clinical attachment loss	up to 6 months	Distance from the cement-enamel junction to the base of the periodontal pocket will be measured using a periodontal probe
Recession width (RW)	up to 6 months	Recession width (W) measured at the widest point (it is the distance between the mesial gingival margin and the distal gingival margin of the tooth) using a periodontal probe
Recession height (RH)	up to 6 months	It will be measured from the cementoenamel junction to the Gingival Margin (GM), parallel to the long axis of the tooth starting from the most apical point of the recession using a William's graduated periodontal probe
Width of keratinized gingiva (KT)	up to 6 months	Width of keratinized gingiva will be measured as the distance from the gingival margin to the mucogingival junction

Trial Locations

Locations (1)

Faculty of Dentistry, Alexandria University; 🇪🇬 Alexandria, Egypt