The extent of intimal hyperplasia and atherogenesis in bypass vein grafts following different surgical preparation techniques

Not Applicable

Completed

• Conditions: Coronary artery disease; Circulatory System; Chronic ischaemic heart disease

• Registration Number: ISRCTN10567790
• Lead Sponsor: niversity Hospitals Bristol NHS Foundation Trust (UK)

Brief Summary

2021 non-peer-reviewed results in preprint in 10.22541/au.161080810.02977290/v1 (added 11/02/2021)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2009-04-30
• Study Completion: 2015-07-01
• Last Update Posted: 22 February 2021

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 96

Inclusion Criteria

Current inclusion criteria as of 08/11/2010:
Male and female patients (aged 18 years and older) undergoing first time elective (standard or urgent priority) coronary artery bypass graft (CABG) at the Bristol Royal Infirmary having one or more saphenous vein grafts will be invited to take part in the study.

Initial information at time of registration:
Male and female patients (aged 18 years and older) undergoing first time elective (standard or urgent priority) coronary artery bypass graft (CABG) at the Bristol Royal Infirmary having one or more vein grafts will be invited to take part in the study.

Exclusion Criteria

Current exclusion criteria as of 30/08/2012:
1. Need for emergency CABG
2. Need for an additional procedure such as valve replacement
3. Ejection fraction less than 30%
4. Congestive cardiac failure
5. Peripheral vascular disease affecting the leg(s)
6. Pre-operative serum creatinine greater than 104 µmol/l
7. Allergy to iodinated contrast media
8. Unwillingness to participate in follow-up
9. Aged less than 18 years
10. Previous cardiac surgery

Previous exclusion criteria between 08/11/2010 and 30/08/2012:
6. Pre-operative serum creatinine greater than 120 µmol/l

Initial information at time of registration:
1. Need for emergency CABG
2. Need for an additional procedure such as valve replacement
3. Ejection fraction less than 35%
4. Congestive cardiac failure
5. Peripheral vascular disease
6. Pre-operative serum creatinine greater than 120 µmol/l
7. Allergy to iodinated contrast media
8. Unwillingness to participate in follow-up
9. Aged less than 18 years

Study & Design

• Study Type: Interventional
• Study Design: Not specified