A prospective Observational study to assess and correlate the changes in the levels of serum amylase, C-reactive protein and procalcitonin with severity and its significance in cases of abdominal trauma.

Caglar Kuas MD et al (2023), conducted a study on the diagnostic value of laboratory tests in detecting solid organ injuries in patients with blunt abdominal trauma on 323 patients in which 118 (36%) were male. There were 283 patients who underwent CT. SOI was detected in 18 (6%) patients. Abnormal alanine aminotransferase, aspartate aminotransferase, amylase and lipase tests were found to be statistically significant in predicting SOI. However, none of the tests were found to have sufficient sensitivity and specificity.

Cai-Fung xi (2022) To analyze early changes in white blood cells (WBCs), C-reactive protein (CRP) and procalcitonin (PCT) in children with multiple trauma, before secondary inflammation develops Secondary to multiple trauma, PCT levels increased in more patients, even if their WBC and CRP levels remained unchanged.

Maier, Marcus MD et al (2009) studied on serum Procalcitonin Levels in Patients With Multiple Injuries Including Visceral Trauma from 74 patients with multiple injuries showed that PCT significantly increased during the first two posttraumatic days in patients with severe multiple injuries as compared with patients with identical Injury Severity Score but without abdominal injury assessment of serum PCT seems to be significantly increased after abdominal trauma in severe multiple traumatized patients and may serve as a useful biomarker to support other diagnostic methods including ultrasound and CT scan. Although elevated levels of PCT during the first 2 days after trauma are more likely to be indicative of traumatic impact than of an ongoing status of sepsis,

multiple events such as surgery, massive transfusion, and intensive care

therapy might influence the PCT concentration.