NL-OMON38316已完成不适用
A study to evaluate the response of whole blood stimulation with lipopolysaccharide or other inducers and its in vitro inhibition in healthy volunteers, and patients with a chronic inflammatory condition - LPS-pilot healthy volunteers/patients
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 250
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •healthy males
- •healthy female volunteers: pre- and post-menopausal
- •patients with rheumatoid arthritis: active disease and with or without treatment with MTX
- •patients with Crohn's disease: clinically confirmed diagnosis of disease
- •patients with psoriasis: clinically confirmed diagnosis of disease, PASI score>5
- •patients with asthma: clinically confirmed diagnosis of disease
- •patients with proven atherosclerotic disease
排除标准
- •general: any clinically significant disorder (current or past medical history or physical examination) that in the opinion of the investigator precludes study participation
- •patients: clinically significant abnormalities and recent treatment with anti-TNF therapy
研究者
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