Qing-Xin Jie-Yu Granules on cardiopulmonary function for patients with heart failure with preserved ejection fraction: a randomized controlled trial

Xiyuan Hospital, China Academy of Chinese Medical Sciences0 个研究点开始时间: 待定最近更新: 2023年2月20日

试验速览

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•1. Both genders aged 40-70 years;
•2. Patients with chronic heart failure, NYHA II-III,can complete cardiopulmonary exercise test, whose medications had not been adjusted whthin 2 weeks;
•3. LVEF >= 50%;
•4. NT-proBNP >= 400pg/mL;
•5. Patients signed the written informed consent.

•1. LVEF < 50% at any time in the past;
•2. Solely right heart failure due to lung disease;
•3. Short breath caused by non-cardiac diseases, such as lung disease, anemia, severe obesity, primary valvular heart disease, and cardiomyopathy;
•4. Patients with cardio-cerebrovascular disease are planed to undertake revascularization therapy in three months;
•5. Patients with serious primary diseases, such as liver, kidney and hematopoietic system, psychosis and severe neurosis;
•6. Patients with uncontrolled hypertension(systolic pressure >= 160mmhg, or diastolic pressure >= 100mmhg);
•7. Recent recurrence of malignant arrhythmia (paroxysmal ventricular tachycardia);
•8. Pregnant, planned pregnant or lactating women
•9. Those who participated in other clinical trials in the past 1 month;
•10. Allergic constitution or allergy to known ingredients of the test drug.

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