CBT to Treat Depression in Renal Patients

Not Applicable

• Conditions: Depression; End Stage Renal Disease

• Registration Number: NCT00530296
• Lead Sponsor: Federal University of São Paulo

Brief Summary

The purpose of this study is to determine whether Cognitive Behavioral Therapy is effective in the treatment of depression in patients with end-stage renal disease in hemodialysis therapy

Detailed Description

Depression is a persistent problem among patients with end-stage renal disease and it does not tend to improve over time. The implementation of effective interventions to treat and prevent recurrence of depressive episodes is needed. The objectives of this study are: 1)the detection of Major Depression in hemodialysis patients; 2)to allocate patients with depression in two groups: structured program of treatment with CBT (group therapy)and control group (conventional psychotherapy at the dialysis unit); and 3)to verify whether after 3 months of CBT there was a remission of depressive symptoms and a improvement of the quality of life in the CBT group.

Study Timeline

• Study Start: 2005-06
• Status Verified: 2007-09
• Study First Submitted: 2007-09-14
• Study First Submitted QC: 2007-09-14
• Last Update Submitted: 2007-09-14
• Study First Posted: 2007-09-17
• Last Update Posted: 2007-09-17
• Study Completion: 2008-06

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 80

Inclusion Criteria

• Patients with a diagnosis of Chronic renal disease (end stage) in hemodialysis for at least 3 months
• Diagnosis of Major depression disorder (4 or more clinical criteria in MINI and a BDI score of 10 or more)

Exclusion Criteria

• Patients in process of renal transplant with (living donor)
• Psychiatric comorbidity
• Cognitive impairment or mental retardation
• Current substance abuse
• Heart failure, angina pectoris, arrhythmias

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Mini International Neuropsychiatric Interview (MINI-DSM-IV) Beck Depression Inventory (BDI)	Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention)

Secondary Outcome Measures

Name	Time	Method
Kidney Disease and Quality of Life Short-form (KDQOL-SF)	Baseline; 3 months (end of intervention); follow-up (6 months after the end of the intervention)

Trial Locations

Locations (1)

Priscila Silveira Duarte; 🇧🇷 Sao Jose do Rio Preto, Sao Paulo, Brazil