Detection of primary hyperoxaluria in patients with recurrent kidney stones

• Conditions: hyperoxaluria; oxalate kidney stones; 10027424; 10046708

• Registration Number: NL-OMON35996
• Lead Sponsor: Academisch Medisch Centrum

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 29 April 2024

Recruitment & Eligibility

• Status: Pending
• Sex: Not specified
• Target Recruitment: 250

Inclusion Criteria

Patients with recurrent episodes of kidney stones

Exclusion Criteria

Secundary hyperoxaluria caused by short bowel syndrome or inflammatory bowel disorders.

Study & Design

• Study Type: Observational invasive
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Measurement of oxalate, glycolate and L-glycerate in a urine sample, and DNA<br /><br>diagnosis of the AGXT gene for primary hyperoxaluria type 1 or the GRHPR gene<br /><br>for primary hyperoxaluria type 2 if applicable.</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Estimation of kidney function in patients with recurrent kidney stones</p><br>