Impact of Hospital Admission on Patients With Dementia
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 413
- 主要终点
- Mortality during hospitalization and at follow-up
研究概览
简要总结
People with dementia have complex medical, social, and psychological needs and can be exacerbated by physical illness and the complex relationships between health care systems, patients and their families or caregivers. They are a vulnerable and fragile population that differs significantly from the population without dementia. Therefore, the investigators propose the following objectives: 1. To describe the evolution of dementia patients admitted during the study period in two hospitals in the Basque Health Service-Osakidetza and complications associated with such admissions. 2. To compare with a control group (matched by type of pathology, age and sex and adjusting for other clinical variables (severity of dementia ...) the patient's condition before and after admission, in terms of quality of life, dependency, instrumental activities of daily living and severity of dementia. 3. To compare the length of stay, complications, mortality rate, the degree of dependency and quality of life of patients with dementia compared to those without dementia, matched by groups of pathologies, gender and age.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •For the patients with dementia cohort, the inclusion criteria were: (a) Being patient aged over 75 years; (b) having been diagnosed with dementia according to the Diagnostic and Statistical Manual for Mental Disorders-IV (American Psychiatric Association, 1994) by any of the psychiatrists; (c) having received inpatient treatment by the time of the study in the hospital//with an unplanned medical admission to any medical speciality in the Galdakao-Usansolo Hospital (d) agreeing to participate voluntarily and providing written informed consent. Patients with dementia were included if a caregiver agreed to participate voluntarily. Caregiver is defined as any person who cares for a needy person in his or her direct environment on a regular basis and more or less as a matter of course. The caregiver is related (family, friend...) to the person receiving care and is not a professional caregiver (Shoenmakers et al., 2010).
- •For the cognitive intact patients cohort, the inclusion criteria were patients without dementia admitted in the hospital by the time of the study, matched with patients with dementia, after controlling for age, gender and types of pathologies.
排除标准
- •Patients with dementia (or caregivers) were excluded if they did not provide inform consent.
- •The exclusion criteria for patients without dementia were disorders interfering with psychometric assessment, or not given written informed consent.
结局指标
主要结局
Mortality during hospitalization and at follow-up
时间窗: Up to 3 months
In-hospital mortality, and at follow-up: information on survival status of the patients was collected during hospitalization and assessed 3 months after discharge by telephone interview to patients or caregivers.
次要结局
- The Alzheimer's Disease Test (AD8)(Up to 3 months)
- The Quality of Life in Alzheimer's disease (QOL-AD)(Up to 3 months)
- Diagnosis(Up to 3 months)
- Body Mass Index (BMI)(Up to 3 months)
- Assessment of Performance in Basic Activities of Daily Living: Barthel Index(Up to 3 months)
- Nutritional status(Up to 3 months)
- Pressure Ulcer risk: the Braden Scale and the Gosnell Scale were employed.(Up to 3 months)
- Instrumental Activities of Daily Living (IADL)(Up to 3 months)
- EuroQoL 5-domain for Health-related quality of life (EQ-5D) (EuroQoL Group, 1990).(Up to 3 months)
- Caregiver's burden was evaluated with the Zarit Scale(Up to 3 months)
- Level of consciousness: The Glasgow Coma Scale (GCS)(Up to 3 months)
研究者
Josune Martin Corral
PhD
Hospital Galdakao-Usansolo