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Clinical Trials/NCT04190771
NCT04190771
Completed
N/A

Efficacy of a Multicomponent Intervention for Fibromyalgia Based on Physical Activity, Psychological Support, and Nature Exposure (NAT-FM)

Hospital Universitari Vall d'Hebron Research Institute1 site in 1 country169 target enrollmentSeptember 1, 2019
ConditionsFibromyalgia

Overview

Phase
N/A
Intervention
Not specified
Conditions
Fibromyalgia
Sponsor
Hospital Universitari Vall d'Hebron Research Institute
Enrollment
169
Locations
1
Primary Endpoint
Revised Fibromyalgia Impact Questionnaire (FIQR)
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

The main objective of this study is to analyse the efficacy of the NAT-FM multicomponent treatment program as coadjuvant of treatment-as-usual (TAU) compared to TAU alone.

In this Randomized Controlled Trial (RCT), in addition to evaluating the clinical effects of NAT-FM treatment in the short- and long-term, the research team will seek to identify relevant moderators and mediators of clinical change.

Detailed Description

* This is a two-arm RCT focused on the safety and potential efficacy of the multicomponent program NAT-FM as coadjuvant of treatment-as-usual (TAU) vs. TAU alone. * NAT-FM combines Classical Structural Assessment (CSA) and Ecological Momentary Assessment (EMA) to obtain more reliable information about the dynamics of the variables to be evaluated, to record the affective and cognitive impact of each activity, and to explore its potential delivery in real-world clinical practice. * The main hypothesis is that improvement on functional impairment of patients with fibromyalgia can be achieved by the direct intervention on mechanisms such as self-efficacy and pain catastrophizing.

Registry
clinicaltrials.gov
Start Date
September 1, 2019
End Date
February 29, 2020
Last Updated
5 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Eligibility Criteria

Inclusion Criteria

  • Adults from 18 to 75 years-old.
  • 1990 American College of Rheumatology (ACR) classification criteria + the 2011 modified ACR diagnostic criteria for fibromyalgia
  • Able to understand Spanish and accept to participate in the study.

Exclusion Criteria

  • Participating in concurrent or past RCTs (previous year).
  • Comorbidity with severe mental disorders (i.e. psychosis) or neurodegenerative diseases (i.e. Alzheimer) that that would limit the ability of the patient to participate in the RCT.

Outcomes

Primary Outcomes

Revised Fibromyalgia Impact Questionnaire (FIQR)

Time Frame: Through study completion, an average of 9 months

The FIQR comprises three dimensions: physical dysfunction (scores from 0 to 30), overall impact (scores from 0 to 20), and intensity of the symptoms (scores from 0 to 50) is used to measure the impact generated by FM during the last week. It consists of 21 items, which are answered on a numerical rating scale of 11 points (from 0 to 10). Total scores can range from 0 to 100, with higher scores reflecting greater deterioration.

Secondary Outcomes

  • Tampa Scale for Kinesiophobia (TSK-11)(Through study completion, an average of 9 months)
  • Hospital Anxiety and Depression Scale (HADS)(Through study completion, an average of 9 months)
  • Pain Catastrophizing Scale (PCS)(Through study completion, an average of 9 months)
  • Personal Perceived Competence Scale (PPCS)(Through study completion, an average of 9 months)
  • Perceived Stress Scale (PSS)(Through study completion, an average of 9 months)
  • Cognitive Emotion Regulation Questionnaire (CERQ)(Through study completion, an average of 9 months)
  • Rosenberg Self-Esteem Scale (RSES)(Through study completion, an average of 9 months)
  • Ecological Momentary Assessment (EMA)(Through intervention completion, an average of 3 months)
  • Positive and Negative Affect Schedule (PANAS)(Through study completion, an average of 9 months)

Study Sites (1)

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