Can hypnosis be used to manage breathlessness and anxiety in people with severe COPD?

Not Applicable

Completed

• Conditions: Dyspnea (breathlessness) in patients with severe chronic obstructive pulmonary disease (COPD); Respiratory

• Registration Number: ISRCTN10029862
• Lead Sponsor: Bligny Hospital Center

Brief Summary

2020 Results article in https://doi.org/10.2147/COPD.S267019 results (added 23/10/2020) 2022 Protocol article in https://doi.org/10.1183/23120541.00565-2021 (added 28/02/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2020-01-07
• Study Completion: 2020-02-20
• Last Update Posted: 13 March 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 21

Inclusion Criteria

1. Aged 35-80 years
2. Affiliated to a Social Security scheme or beneficiary of such a scheme
3. Absence of neurological disease interfering with the passing of tests
4. Capable of giving free, informed consent.
5. Severe COPD with dyspnea and distension
6. Hospitalized, with or without a tracheotomy
7. Non-obese
8. Predicted FEV1 <60% and FEV/FVC <70%, with distension evidenced by chest x-ray or predicted TLC >120% in pulmonary function tests
9. Severity marked by ongoing hospitalization, with at least one prior instance of decompensation
10. Dyspneic, with resting Borg Scale score =3
11. Not having yet participated in the complementary care protocol offered by the hospital, a pulmonary rehabilitation program (PRP) protocol, or any hypnosis protocol

Exclusion Criteria

1. Pregnancy
2. Mechanical ventilation during the session
3. Known severe cardiac insufficiency
4. Known severe pulmonary arterial hypertension
5. Cancer diagnosis
6. Significant cognitive impairment, hypercapnic encephalopathy or confusional syndrome
7. Deafness
8. Anemia (hemoglobin =8 g/dl)
9. Psychotic pathology
10. Anti-epileptic treatment

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety assessed using the STAI-6 questionnaire at baseline and immediately after intervention

Secondary Outcome Measures

Name	Time	Method
<br> 1. Respiratory rate in cycles/min measured manually, following the accepted standard procedure, at baseline and immediately after intervention<br> 2. Oxygen saturation (SpO2) measured with a pulse oximeter at baseline and immediately after intervention<br>