Molecular Mechanism Identification in Inherited Arrhythmias and Valvulopathies From Induced Pluripotent Stem Cells

Nantes University Hospital1 个研究点分布在 1 个国家目标入组 20 人开始时间: 2011年11月最近更新: 2014年11月7日

适应症

试验速览

阶段: 不适用
状态: 终止
发起方: Nantes University Hospital
入组人数: 20
试验地点: 1
主要终点: Production of cardiomyocytes modele from skin fibroblast of arrhythmic patient

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The recent developments of research on iPS (induced pluripotent stem) cells lead to the establishment of mature cell lines such as cardiomyocytes or valvular interstitial cells with genetic and cellular characteristics of the donors. These cells represent a biological material more readily available to identify the pathophysiological mechanisms involved in the diseases of BrS or ERS patients, which will lead to the identification of genetic markers.

研究设计

研究类型: Interventional
盲法: None

入排标准

年龄范围: 22 Years 至 60 Years（Adult）
性别: All
接受健康志愿者: 是

入选标准

未提供

排除标准

未提供

结局指标

主要结局

Production of cardiomyocytes modele from skin fibroblast of arrhythmic patient

次要结局

Production of valve interstitial cells modele from skin fibroblast of patient with a valvulopathy

研究者

发起方

Nantes University Hospital

申办方类型

Other

责任方

Sponsor

研究点 (1)

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