An attempt of individualized administration of thiopurine by measuring metabolites and metabolic enzyme activities
Not Applicable
Recruiting
- Conditions
- ulcerative colitis, Crohn's disease
- Registration Number
- JPRN-UMIN000047053
- Lead Sponsor
- Kitasato University Kitasato Institute Hospital, Center for Advanced IBD Research and Treatment
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 50
Inclusion Criteria
Not provided
Exclusion Criteria
When the physician in charge considers it inappropriate from the viewpoint of human rights protection and the purpose of the research, taking into consideration the health condition, symptoms, age, capacity to consent, and trust relationship with the physician in charge.
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Correlation of NUDT enzyme activity level with dTG and thiopurine dosage
- Secondary Outcome Measures
Name Time Method Explore factors that regulate NUDT15 enzyme activity, especially factors other than the NUDT15 polymorphism.