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Study to evaluate the effectiveness and safety of drug- oral tofacitinib in patients with Parthenium dermatitis

Not Applicable
Conditions
Health Condition 1: L237- Allergic contact dermatitis due toplants, except food
Registration Number
CTRI/2023/10/058514
Lead Sponsor
AIIMS, New Delhi
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

1. Patients with airborne contact dermatitis with positive patch test to Parthenium, having a Parthenium Dermatitis Severity Score (PDSS) of more than or equal to 10.

2. Patients more than or equal to 18 years of age.

3. Consenting patients who are willing to undergo treatment and report for follow up.

Exclusion Criteria

1. Patients with significant and active liver, renal or haematological disease.

2. Patients < 18 years of age.

3. Pregnant and lactating females.

4. Patients with active or latent TB.

5. Patients with a lymphocyte count less than 500 cells/mm3, an absolute neutrophil count less than 1000 cells/mm3, or hemoglobin level less than 9 g/dL.

6. Patients with active infections.

7. Patients with history of thromboembolic phenomenon or on anticoagulants

8. Patients on immunosuppressive therapy in the last 4 weeks.

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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