evaluation of the effect of Coritrip on the improvement of symptoms of gastroesophageal reflux disease

Phase 3

Conditions: gastroesophageal reflux disorder.
Gastro-esophageal reflux disease with esophagitis
K21.0

Registration Number: IRCT20221102056376N1

Lead Sponsor: Fasa University of Medical Sciences

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: All

Target Recruitment: 76

Inclusion Criteria

Organic causes of indigestion have been ruled out by the doctor.
Do not have a history of allergy to medicinal plants used in this study.
Not pregnant or breastfeeding and not planning to become pregnant during the study.
Do not have chronic liver, kidney or cancer diseases.
Not taking anticoagulant drugs such as warfarin, plavix, aspirin and other chemical or herbal drugs that interfere with the studied compound or disrupt the results of the plan.
The patient has been diagnosed with GERD by a doctor during endoscopy.
Having ROME IV criteria to enter the study

Exclusion Criteria

Incidence of drug allergy
Diagnosis of organic dyspepsia during study
The patient's unwillingness to continue the plan
Starting to take drugs such as anticoagulants such as warfarin, Plavix, aspirin and other drugs that interfere with the herbs in the composition or have a possible positive or negative effect on functional indigestion.
Pregnancy
contracting covid19 or any disease for which the doctor required the patient to withdraw from the plan. The location of the study is the clinic and office of internal medicine and gastroenterology specialists in Fasa city.

Study & Design

Study Type: interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Quality of life (SF-36 questionnaire). Timepoint: 30, 60 days from the first day of study. Method of measurement: SF-36 questionnaire.;Abdominal bloating intensity and rate, early satiety rate, stomach rumbling rate and burping rate. Timepoint: 30, 60 days from the first day of study. Method of measurement: questionnaire.

Secondary Outcome Measures