Comparison of between techniques for EUS-guided tissue acquisitio
- Conditions
- Neoplasms
- Registration Number
- KCT0004678
- Lead Sponsor
- Hallym University Medical Center-Dongtan
- Brief Summary
The median quality score of the histological samples was significantly higher in the torque and fanning group than in the standard group (P <0.001). Furthermore, the torque technique provided improved sensitivity of 93.38% and accuracy of 94.30%. The standard technique provided diagnostic sensitivity of 68.84% and accuracy of 72.96%, while the fanning technique showed sensitivity of 91.85% and accuracy of 93.04%.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Completed
- Sex
- All
- Target Recruitment
- 155
1. Consecutive patients who will be referred to each medical center for EUS-FNB to evaluate pancreatic solid masses
2. Age of 19 or more years old
3. Able to voluntarily agree to participate and to sign informed consent
4. Willingness to participate and sign the informed consent agreement.
1) if the mass had only a cystic component without a solid component suspected with malignant transformation
2) if the coagulation parameters were abnormal (international normalized ratio >1.5 or platelet count <50,000 cells/cmm
3) postponing the antithrombotic therapy was impossible
4) if the patient had cardiopulmonary instability
5) pregnancy
Study & Design
- Study Type
- Interventional Study
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method the proportion of achievement of true diagnosis without ROSE on the first pass
- Secondary Outcome Measures
Name Time Method the procurement rate of optimal histologic cores (possible for IHC stain);Diagnostic yield: sensitivity, specificity, positive predict value, negative predict value;Rate of technical failure;Procedure/Device related major adverse events