Evaluation of the Effect of Smokeless Tobacco on Anterior Segment Parameters
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 107
- 试验地点
- 1
- 主要终点
- Central Corneal Thickness (CCT)
研究概览
简要总结
Observational, comparative, cross-sectional study
详细描述
To evaluate the acute and chronic effects of smokeless tobacco (ST) on the anterior segment parameters using optical biometry. Observational, comparative, cross-sectional study Place and Duration of Study: Department of Ophthalmology, Kahramanmaras Sutcu Imam University.
The study included 53 right eyes of 53 subjects (study group), who used ST and 54 right eyes of 54 healthy subjects without ST (control group). Following a full ophthalmological examination, baseline measurements were taken with optical biometry and these measurements were repeated at 5, 30 and 60 mins after using ST.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 26 Years 至 49 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •A subject who use ST
- •A subject who was not using ST
排除标准
- •Refractive disorder
- •Systemic chronic disease (diabetes, hypertension, neurological, etc.)
- •Ocular trauma
- •Ocular surgery
- •Optic disc abnormalities
- •Congenital anomaly
结局指标
主要结局
Central Corneal Thickness (CCT)
时间窗: Baseline to 60 minutes after intervention
Change in Central Corneal Thickness (CCT
Axial Length (AL)
时间窗: Baseline to 60 minutes after intervention
Change in Axial Length (AL)
Pupillary diameter (PD)
时间窗: Baseline to 60 minutes after intervention
Change in Pupillary diameter (PD)
Anterior chamber deep (ACD)
时间窗: Baseline to 60 minutes after intervention
Change in Anterior chamber deep (ACD)
Lens thickness (LT)
时间窗: Baseline to 60 minutes after intervention
Change in Lens thickness (LT)
次要结局
未报告次要终点
研究者
Abdullah Beyoğlu
Assist of Prof
Kahramanmaras Sutcu Imam University