An Open, Non-Randomized, Single Arm, Single Centric Clinical Trial To Evaluate The Effectiveness Of Pala (Citramutti) Madakku Thailam In The Management Of Asthi Vatham (Osteoporosis) Among Out-Patients Attending Ayothidoss Pandithar Hospital, National Institute Of Siddha

Introduction:

This is an open Non Randomised clinical trial thatevaluates therapeutic effectiveness of siddha formulation Pala (Citramutti)Madakku Thailam in the management of Asthi vatham (Osteoporosis)patients through improvement of T scores in Bone Mineral Densitometer Scanbefore and after treatment. Worldwide,it is estimated that 1 in 3 women above the age of 50 will experienceosteoporotic fractures, as well as 1 in 5 men. According to the Siddha, Asthivatham (Osteoporosis) can betreated using the trial drug. The major ingredient Sida cordifolia werefound to be effective in increasing the bone density in patients with  osteoporosis in several studies. It also hasrich source of phytoestrogens which inhibit bone resorption and negate the boneresorption effects. Milk is an excellent calcium source and also suppresses thebone resorption in Osteoporosis. Sesamum indicum also exhibits pro-osteoblasticand anti-osteoclastic activity.

Objective: To evaluate the therapeutic effectiveness of Pala(Citramutti) Madakku Thailam in the management of Asthivatham (Osteoporosis) usingT scores of Bone Mineral Densitometer Scan before and after treatment.

Materials and Methods: An Open Non Randomised Clinical Trial witha total of 10 patients diagnosed of Asthi vatham (Osteoporosis) with ageof above 40 years willing to participate in the study ,by signing the informedconsent form will be enrolled in the study. The trial drug will be given for 90days along with 1 month follow up.

Result: The average T scores before and after treatment will be statisticallyanalysed.

Keywords: PalaMadakku Thailam, Osteoporosis