A comparison of conventional adult out-of-hospital cardiopulmonary resuscitation against a concept with mechanical chest compressions and simultaneous defibrillation - LINC study

Recruiting

• Conditions: circulatory arrest; sudden cardiac arrest; 10007521

• Registration Number: NL-OMON33629
• Lead Sponsor: Jolife AB

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Last Update Posted: 13 May 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: Not specified
• Target Recruitment: 800

Inclusion Criteria

Circulatory arrest

Exclusion Criteria

1. Traumatic cardiac arrest, including hanging
2. Age believed to be less than 18 years (no upper limit)
3. Known pregnancy
4. Defibrillated before LUCAS Chest Compressions System arrives at scene
5. Patients body size not fitting the LUCAS Chest Compression System

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Page number 13 of the study protocol<br /><br><br /><br>8.1 PRIMARY ENDPOINT<br /><br>• Four hour survival from successful restoration of spontaneous circulation.<br /><br>This will generally mean survival to reach Intensive Care Unit (ICU) or Cardiac<br /><br>Care Unit (CCU).</p><br>

Secondary Outcome Measures

Name	Time	Method
<p>Page number 12 of the study protocol<br /><br><br /><br>8.2 SECONDARY END POINTS<br /><br>• Restoration of spontaneous circulation (ROSC) defined as spontaneous palpable<br /><br>pulse.<br /><br>• Arrival to the emergency room with spontaneous palpable pulse<br /><br>• Survival to discharge from Intensive Care Unit (ICU) without severe<br /><br>neurological impairment (Cerebral Performance Category (CPC) 1 or 2).<br /><br>• Survival to hospital discharge without severe neurological impairment (CPC 1<br /><br>or 2).<br /><br>• Survival 1 and 6 months after cardiac arrest without severe neurological<br /><br>impairment (CPC 1 or 2).</p><br>