Comparative evaluation of Hyaluronic acid plus Gelatin sponge, Risedronate plus Gelatin sponge and Gelatin sponge on healing of Periapical lesion using CBCT - An Invivo study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Absence of swelling, pain, pus discharge, sinus opening, Mobility, Tenderness to percussion
研究概览
简要总结
This study is a randomized, double blinded, parallel arm design comparing the effect of hyaluronic acid and Risedronate gel with gelatin sponge on healing of periapical lesions using cone beam computed tomography (CBCT) carried out in Tamil Nadu Government Dental college and Hospital among 25 patients of age group from 20 to 40 years of both gender with periapical lesion size ranging from 10 to 20 mm. The primary outcome should be absence of pain, swelling, pus discharge, sinus opening, tenderness to percussion. The secondary outcome being radiographic evidence of increase in bone density and reduction in size of the lesion at the end of 3, 6, 9 and 12 months.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 盲法
- Participant and Outcome Assessor Blinded
入排标准
- 年龄范围
- 20.00 Year(s) 至 40.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients between 20-40 years of age from both the gender, Periapical lesions involving maxillary and mandibular incisors of strictly endodontic origin, The diameter of the bone defect of 10 -20 mm, Patients willing for voluntary participation & have signed informed consent, Patients with good oral hygiene, Systemically healthy patients.
排除标准
- •periodontal tooth with poor prognosis, tooth with pathosis with vertical root fracture, patients with bleeding disorders, patients showing poor oral hygiene maintenance, Patients with use of tobacco or tobacco related products, Pregnant / Lactating patients, Patients with known systemic diseases, Patients with any known allergies, Patients with any known metabolic disorders.
结局指标
主要结局
Absence of swelling, pain, pus discharge, sinus opening, Mobility, Tenderness to percussion
时间窗: 1,3,6,9 and 12 months
次要结局
- Bone density evaluation of the Periapical region was done after surgery using CBCT(6 and 12 months)
研究者
Akshaya S P
Tamilnadu Government Dental College and Hospital