The efficacy of vitamin D administration in non-alchoholic fatty liver disease(NAFLD)
Not Applicable
- Conditions
- onalcoholic fatty liver disease (NAFLD).Nonalcoholic fatty liver disease (NAFLD
- Registration Number
- IRCT2015102624725N1
- Lead Sponsor
- Vice Chancellor for Research Mazandaran University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Complete
- Sex
- All
- Target Recruitment
- 40
Inclusion Criteria
Inclusion Criteria: ALT rising equals or more than 2times of normal level; probable diagnosis of Nonalcoholic Steatohepatitis and rule out of other hepatic-enzymes rising causes such as viral and autoimmune hepatitis; age more than 18 years; serum vitamin D level less than 30 nanogram per mililiter
Exclusion Criteria
hepatic cirrhosis; pregnancy or breast-feeding; alcohol use ; substance abuse;vitamin D administration in 6 months ago, weight loss more than 5% in 1 year ago; newly-diagnosed diabetes (in the recent 1 year) which needs treatment: antioverweight medication ; hypercalcemia; chronic renal disease; life-threatening cardiopulmonary diseases ; hyperlipidemia which needs medication; medications which affect on hepatic enzymes
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method The level of aminotransferases. Timepoint: 3th and 6th month. Method of measurement: biochemical.;Fibroscan and BMI. Timepoint: 3th and 6th month for BMI and 6th month for fibroscan. Method of measurement: fibroscan and anthropometric measurement( kg/m2).
- Secondary Outcome Measures
Name Time Method