NCT01102205已完成不适用
Evaluation of Oxidative Stress and Effect of Levothyroxine Treatment on Oxidative Stress in Hashimoto Disease
Vakif Gureba Training and Research Hospital1 个研究点 分布在 1 个国家目标入组 130 人开始时间: 2010年4月最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 130
- 试验地点
- 1
- 主要终点
- Poxidative stress markers
研究概览
简要总结
Oxidative stress leads to or accompanies with numerous disease. Oxidative balance in subclinical hypothyroid or euthyroid state in Hashimoto disease are not known. Effect of levothyroxine therapy on oxidative balance are also not known in hashimoto disease.
详细描述
oxidative stress markers will be measured initially(TAS,TOS,OSI,PARAOXONASE,ARYLESTERASA,PON1 PHENOTYPİNG,LİPİDPEROXİD).After 3 months therapy with levothyroxine measurements will be repeated except PON1 phenotyping.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 95 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •age more than 18 years
排除标准
- •inability to give a written consent
- •other conditions and drug usage affect oxidative stress
结局指标
主要结局
Poxidative stress markers
时间窗: After levotren therapy
次要结局
未报告次要终点
研究者
Mehmet Ali Cikrikcioglu
Vakif Gureba TRH
Vakif Gureba Training and Research Hospital
研究点 (1)
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