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A trial comparing whether giving less intravenous fluid than usual in mechanically ventilated children is associated with better outcomes.

Phase 1
Conditions
Health Condition 1: J969- Respiratory failure, unspecified
Registration Number
CTRI/2023/10/059358
Lead Sponsor
Dr Suresh Kumar
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Status
ot Yet Recruiting
Sex
Not specified
Target Recruitment
0
Inclusion Criteria

All children between the age group of 3 months to 12 years who are mechanically ventilated (with anticipated mechanical ventilation for =48 hours) and have been haemodynamically stable for 6 hours prior to enrolment (no requirement for fluid boluses or increase in vasoactive drugs over the past 6 hours).

Exclusion Criteria

1.Haemodynamically unstable children (requirement of fluid boluses or increase in vasoactive drugs over the past 6 hours)

2.Diarrhoea with dehydration

3.Acute kidney injury

4.Need of renal replacement therapy at admission

5.Known congenital or acquired cardiac disease

6.Chronic liver, lung, or kidney disease

7.Inborn errors of metabolism

8.Diabetic ketoacidosis

9.Known syndrome of inappropriate ADH secretion (SIADH), cerebral salt wasting (CSW) or diabetes insipidus

10.Consent refusal

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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