Neuroscience Pain Education in Patients with Chronic Low Back Pain

Not Applicable

Completed

• Conditions: Manual Therapy; Neuroscience Pain Education; Chronic Low Back Pain
• Interventions: Other: manual therapy; Other: neuroscience pain education; Other: home exercises

• Registration Number: NCT03886636
• Lead Sponsor: Kutahya Health Sciences University

Brief Summary

The cognitive educational strategies such as neuroscience pain education, has been a popular and promising technique for treatment patients with chronic pain. However, there are not sufficient randomized controlled and blinded studies to explore clinical effectiveness of these techniques. Therefore, the aim of this study was determining the short- and mid-term effects of neuroscience pain education combined with manual therapy and home exercise on pain level, disability, and kinesiophobia in patients with chronic low back pain.

Detailed Description

Not available

Study Timeline

• Study Start: 2018-02-01
• Primary Completion: 2018-10-30
• Study Completion: 2019-01-01
• Status Verified: 2019-03
• Study First Submitted: 2019-03-19
• Study First Submitted QC: 2019-03-21
• Study First Posted: 2019-03-22
• Last Update Submitted: 2024-10-09
• Last Update Posted: 2024-10-14

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 69

Inclusion Criteria

• Volunteered to participate in the study.
• Patients with 18-65 years
• Had low back pain for at least 6 months,
• Reported pain severity of 5 or greater according to the numeric pain rating scale
• Used pregabalin and gabapentin derivatives,

Exclusion Criteria

• Previous spine or lower extremity surgery
• Severe osteoporosis
• Spondyloarthropathy
• Spondylolisthesis
• Lumbar stenosis
• Systemic inflammatory diseases

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: FACTORIAL

Arm && Interventions

Group	Intervention	Description
Manual therapy group	manual therapy	in Group 2, participants received manual therapy and a home exercise program.
Neuroscience pain education group	home exercises	in Group 1, participants received Neuroscience pain education, manual therapy and a home exercise program.
Neuroscience pain education group	manual therapy	in Group 1, participants received Neuroscience pain education, manual therapy and a home exercise program.
Manual therapy group	home exercises	in Group 2, participants received manual therapy and a home exercise program.
Control group	home exercises	in Group 3, participants received home exercise program only.
Neuroscience pain education group	neuroscience pain education	in Group 1, participants received Neuroscience pain education, manual therapy and a home exercise program.

Primary Outcome Measures

Name	Time	Method
Numeric pain rating scale (NPRS)	Change from Baseline NPRS at 4th weeks and 12th weeks	The NPRS was used to assess the participants' pain levels. In the NPRS, patients are asked to verbally rate the severity of their pain on a scale from 0 to 10. The 11-point numeric scale ranges from '0' representing one pain extreme (e.g. "no pain") to '10' representing the other pain extreme.

Secondary Outcome Measures

Name	Time	Method
Oswestry Disability Index (ODI)	Change from Baseline ODI at 4th weeks and 12th weeks	The participants' level of functioning was evaluated using the Turkish adaptation of the ODI. The scale comprises 10 items, each with 6 options worth 0 to 5 points. For each item, participants are asked to mark the option that best describes their current condition. Each question is scored on a scale of 0-5 with the first statement being zero and indicating the least amount of disability and the last statement is scored 5 indicating most severe disability. The scores for all questions answered are summed, then multiplied by two to obtain the index (range 0 to 100). Zero is equated with no disability and 100 is the maximum disability possible.
Back Performance Scale (BPS)	Change from Baseline BPS at 4th weeks and 12th weeks	The BPS includes five tests of trunk mobility. Each test is scored from 0 to 3 based on the observed level of physical performance, and total score ranges from 0 to 15 points (18). High score indicates poor performance.
Tampa Scale for Kinesiophobia (TSK)	Change from Baseline TSK at 4th weeks and 12th weeks	TSK was used for the assessment of kinesiophobia. The items are rated on a 4-point Likert-type scale (1=definitely disagree, 4=completely agree) and the total score is between 17 and 68 points. Higher total score indicates higher level of kinesiophobia.

Trial Locations

Locations (1)

Yoncali Physical Therapy and Rehabilitation Hospital; 🇹🇷 Kutahya, Turkey