Comparasion of Bio-markers and Neuroimaging Changes Caused by Neuroenflamation After the Aneurysmal Subarachnoid Hemorrhage
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Subarachnoid Hemorrhage, Aneurysmal
- Sponsor
- Bezmialem Vakif University
- Enrollment
- 54
- Primary Endpoint
- Diagnostic marker identification
- Last Updated
- 7 years ago
Overview
Brief Summary
The investigators are planning that can these markers be used a predictive marker at SAH and for this aim we will study both patiens' blood sample and their CT image.
Detailed Description
An ideal marker which could be used clinically should meet numerous criteria, such as high sensitivity or the possibility of easy and quick assessment of its concentration in blood or blood plasma.The Fisher's scale presents an alternative for evaluating patients with subarachnoid hemorrhage . The investigator are going to evaluate both plasma markers and fishers scale at SAH.
Investigators
Eligibility Criteria
Inclusion Criteria
- •Ruptured Subarachnoid Aneursym
Exclusion Criteria
- •without aneursymal sah
- •Patient's positive for rheumatoid factor and anti-CCP or with chronic inflammatory diseases (such as ankylosing spondylitis or rheumatoid arthritis), systemic diseases (such as hypercholesterolemia, hypertension, diabetes mellitus, myocardial infarction, stroke, peripheral artery disease), active infection, a history of term medication, trauma to the hip and smoking were excluded from the study.
Outcomes
Primary Outcomes
Diagnostic marker identification
Time Frame: 24 months
Evaluation of the concentration levels of enflamation markers relation with Sur1 TRPM+ molecules, together with the values of global tests of coagulation system, may serve as a helpful SAH diagnostic marker.