Comparison of the Addition of an Aerosol Mask Above Nasal Canula on Oxygenation in Hypoxemic Failure
Trial Snapshot
- Phase
- Not Applicable
- Sponsor
- Enrollment
- 15
- Locations
- 2
- Primary Endpoint
- Change in PaO2 and PaCO2
Study Overview
Brief Summary
This study will compare the impact of a classical aerosol mask above low-flow nasal cannula on the arterial oxygen tension in patients with COVID-19.
Detailed Description
Hospitalized patients with COVID-19 typically present with hypoxemia. In some patients, hypoxemia can be corrected with low flow nasal cannula. When placed above nasal cannula, some systems have demonstrated their interest in improving the performance of the patient's oxygen delivery. For example, two recent studies have shown that adding a Double-Trunk Mask (DTM) or Surgical Mask (SM) above nasal cannula has the potential to improve the PaO2 despite no change in oxygen output (1, 2) . However, no study has compared the effect on PaO2, of the addition of a classical aerosol mask above nasal canula.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Crossover
- Primary Purpose
- Supportive Care
- Masking
- Single (Outcomes Assessor)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- Not provided
Exclusion Criteria
- •Hypercapnia
Outcomes
Primary Outcomes
Change in PaO2 and PaCO2
Time Frame: 30 minutes
Changes in PaO2 \[ Time Frame: At baseline and 30 minutes after wearing the randomized oxygen delivery system \] Oxygen tension (PaO2) in mmHg will be analyzed from a sample taken from the arterial system
Secondary Outcomes
- Respiratory frequency(1 minute)
Investigators
frédéric Duprez
Deputy director, clinician, laboratory of movement Condorcet Belgium
Laboratory of Movement, Condorcet, Tournai, Belgium