Interventional Study on the Treatment of Uveitis With Vitamin and Unsaturated Fatty Acid Combination Dietary Supplements Through Modulating T Cell Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 7
- 试验地点
- 1
- 主要终点
- Inflammatory factors-Interleukin-17A (IL-17A)
研究概览
简要总结
The goal of this clinical trial is to learn if dietary supplements containing vitamin and unsaturated fatty acid works to intervene T cell inflammatory factor expression in patients with uveitis and healthy subjects in adults.
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •healthy or with uveitis volunteers age 19-65 years.
排除标准
- •abnormal blood glucose, blood pressure, blood lipids, or other systemic diseases should not participate in the study
结局指标
主要结局
Inflammatory factors-Interleukin-17A (IL-17A)
时间窗: 3 weeks
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Interleukin-17A (IL-17A) -producing cells in CD4+ T cells and CD8+ T cells
Inflammatory factors-Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)
时间窗: 3 weeks
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) -producing cells in CD4+ T cells and CD8+ T cells
Inflammatory factors-Interferon gamma (IFN-γ)
时间窗: 3 weeks
Flow cytometry analysis of peripheral blood mononuclear cells (PBMCs) to detect the ratio of Interferon gamma (IFN-γ) -producing cells in CD4+ T cells and CD8+ T cells
次要结局
- Cytokine levels-Interferon gamma (IFN-γ)(3 weeks)
- Cytokine levels-Interleukin-2 (IL-2)(3 weeks)
- Cytokine levels-Interleukin-10 (IL-10)(3 weeks)
- Cytokine levels-Interleukin-17A (IL-17A)(3 weeks)
- Cytokine levels-Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)(3 weeks)
- Cytokine levels-Interleukin-4 (IL-4)(3 weeks)
- Cytokine levels-Interleukin-9 (IL-9)(3 weeks)
- Cytokine levels-Tumor Necrosis Factor alpha (TNF-α)(3 weeks)
研究者
Xiaomin Zhang
Principal Investigator, MD, PhD
Tianjin Medical University