Intermittent Theta Burst Stimulation (iTBS) Transcranial Magnetic Stimulation (TMS) for treatment-refractory Body Dysmorphic Disorder (BDD)

Not Applicable

• Conditions: Treatment-refractory Body Dysmorphic Disorder; Mental Health - Other mental health disorders

• Registration Number: ACTRN12615000737538
• Lead Sponsor: St Vincent’s Hospital, Melbourne.

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2015-07-17
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Stopped early
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

18-65 years.
DSM-5 criteria for BDD, and clinical psychiatric evaluation.
Treatment refractoriness: no response or insufficient response following at least 2 treatments with a selective serotonin reuptake inhibitor (SSRI) at maximum dosage for at least 12 weeks, plus at least 1 Cognitive-Behavioural Therapy (CBT) trial for a minimum of 16 sessions (Phillips, 2008).
20 or higher on the BDD version on the Yale-Brown Obsessive Compulsive Scale for Body Dysmorphic Disorder (BDD YBOCS).

Exclusion Criteria

Active substance abuse, neurological disorder including a history of seizures or epilepsy, pregnancy, or any current medical disorder that may affect cerebral metabolism; or acutel suicidality.

Also: cochlear implants; metallic implants in the brain or elsewhere (splinters, clips, fragments); an implanted neurostimulator (deep brain stimulator, vagal nerve stimulator, epidural/subdural stimulator); cardiac pacemaker or intracardiac line; or medication infusion device.

Study & Design

• Study Type: Interventional
• Study Design: Not specified