A computer-based training to prevent depression and anxiety in oncology patients

Conditions: Cancer

Registration Number: NL-OMON29198

Lead Sponsor: Radboudumc

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Pending

Sex: Not specified

Target Recruitment: 120

Inclusion Criteria

Receiving current cancer treatment
-Patients with a score of 8 or higher in the HADS will be considered for participation in the study (HADS; Zigmond & Snaith, 1983). This cut-off shows good sensitivity and specificity in a somatic patient population (Bjelland et al., 2002)
-Signed informed consent form
-Minimum age of patients is 18 years

Exclusion Criteria

-Impossibility to obtain a valid informed consent
-Insufficient comprehension of the Dutch language
-IQ estimate < 80 points
-Acuteness of symptoms (somatic or psychiatric) that prevent patient from attentively doing the task 20 min per day

Study & Design

Study Type: Interventional

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Anxiety and depressive symptoms measured with the Hospital Anxiety and Depression Scale (HADS; Zigmond & Snaith, 1983)

Secondary Outcome Measures

Name	Time	Method
- Mood: ‘Subjective mood ratings’ before, during, and after the intervention<br>- Repetitive negative thinking: Perseverative Thinking Questionnaire (PTQ; Ehring et al., 2011<br>- Distress: Depression Anxiety Stress Scale-21 (DASS-21, Lovibond & Lovibond, 1995) <br>- Cancer-specific distress: Impact of Event Scale (IES, called Schokverwerkingslijst, Horowitz, Wilner &, Alvarez, 1979; Brom & Kleber, 1985; van der Ploeg, Mooren, Kleber, van der Velden &, Brom, 2004)<br>- General functioning: WHO Disability Assessment Schedule 2.0 (WHODAS, Üstün, Kostanjsek, Chatterji &, Rehm, 2010; WHO, 2018, see http://www.who.int/classifications/icf/more_whodas/en/)<br>- Bias change: trials embedded in the training to assess change in training-congruent bias<br>- Implicit associations: Single-Target Implicit Association Test <br>- Explicit associations: picture (stimuli) ratings<br>- Memory: Recognition task