Prospective Cohort Study of the Ability of MRI/DTI to Diagnose Prostate Cancer in Men Undergoing Prostate MRI
Overview
- Phase
- N/A
- Intervention
- Not specified
- Conditions
- Magnetic Resonance Imaging
- Sponsor
- Rabin Medical Center
- Enrollment
- 200
- Locations
- 1
- Primary Endpoint
- Compare between number of prostate cancer diagnosed by mpMRI to the ones diagnosed by MRI/DTI
- Last Updated
- 8 years ago
Overview
Brief Summary
The purpose of this study is to examine if investigators can improve diagnosis of prostate cancer by using MRI/DTI?
Detailed Description
This is a prospective cohort study of the ability of MRI/DTI to diagnose prostate cancer in men undergoing prostate MRI. Study design: Male adults who are scheduled to undergo MRI of the prostate, for clinical reasons, will be subjected to additional 10 minutes of image acquisition inside the MRI machine. The added MRI/DTI acquisition does not involve injection of additional contrast material. Investigators will compare between ability of the full mp-MRI images to diagnose prostate cancer to that of the MRI/DTI images
Investigators
david margel
Staff Uro-Oncologist
Rabin Medical Center
Eligibility Criteria
Inclusion Criteria
- •Men who are scheduled to undergo MRI of the prostate at the Department of Imaging, in Beilinson Hospital, Rabin Medical Center
- •Men who are willing and able to sign an informed consent form.
Exclusion Criteria
- •Men who cannot complete the full acquisition of the MRI and the MRI/DTI image sequences for any reason.
Outcomes
Primary Outcomes
Compare between number of prostate cancer diagnosed by mpMRI to the ones diagnosed by MRI/DTI
Time Frame: 1 year
Secondary Outcomes
- Compare the correlation of MRI/DTI parameters with prostate cancer diagnosis to the ones measured by mpMRI (ADC, and diffusion weighted images).(1 year)
- Compare between MRI/DTI and MRI ability to identify low-grade and high-grade prostate cancer(1 year)
- Compare between MRI/DTI and MRI in PiRAD grading(1 year)
- Compare between MRI/DTI and MRI in their ability to estimate tumor size.(1 year)