Comparison of the effect of oral clarithromycin with systemic glucantime on the treatment of acute cutaneous leishmaniasis
Phase 1
Recruiting
- Conditions
- Cutaneous Leishmaniasis.Cutaneous leishmaniasis
- Registration Number
- IRCT20180411039265N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
having an indication of systemic treatment in patients with acute cutaneous leishmaniasis
less than 12 weeks of illness
receiving no previous treatment
Exclusion Criteria
Pregnancy
Breastfeeding
Use of other methods of treatment during the course of treatment
Past medical history of any local or systemic disease during the last 2 months
History of intolerance or allergies to macrolides
A significant underlying disease such as heart, renal, or liver diseases.
Use of other treatments before referral
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Percentage of complete recovery of the lesion. Timepoint: Follow-up and assessment of recovery are done every two weeks, and the duration of the therapeutic effect of the lesions is assessed based on changes in the size, extent, redness and firmness of the lesions. The treatment period is considered two month. Patients will also be followed 6 weeks, 3 months and 6 months after the treatment is over. Method of measurement: Measuring size of the lesion with digital caliper.
- Secondary Outcome Measures
Name Time Method