Fatigue and Kinematics During Isometric Activity of the Upper Limbs in Young and Older Adults

Not Applicable

Completed

• Conditions: Fatigue
• Interventions: Other: Isometric activity

• Registration Number: NCT04938791
• Lead Sponsor: Escola Superior de Saude da Cruz Vermelha Portuguesa - Lisboa

Brief Summary

The aim of this study is to understand the relationship between perceived effort and physiological and kinematic variables caused by isometric activity of the upper limbs, as well as its relationship with socio-demographic characteristics, level of activity and quality of life.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2021-06-04
• Study First Submitted QC: 2021-06-16
• Study First Posted: 2021-06-24
• Study Start: 2021-10-01
• Primary Completion: 2022-02-28
• Study Completion: 2022-02-28
• Status Verified: 2022-03
• Last Update Submitted: 2022-03-30
• Last Update Posted: 2022-03-31

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 60

Inclusion Criteria

• Healthy
• Minimum age of 18 years;

Exclusion Criteria

• Unable to provide written consent
• History of heart, cardiovascular and / or respiratory disease,
• Known untreated hypertension, cardiomyopathy, or exercise intolerance
• Presence of cognitive or neurological disorders
• Neuromuscular or orthopaedic disorder that limits the movement of the upper limb to 90° flexion or the maintenance of that position
• BMI ≥ 40

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Isometric activity	Isometric activity	All participants will be included in this arm

Primary Outcome Measures

Name	Time	Method
Change from Baseline in heart rate variability (HRV)	From baseline to end of activity, up to 15 minutes	Interval (in milliseconds) between consecutive heartbeats measured before and during activity to track changes in autonomic function during activity.
Change from Baseline in muscle action potential amplitude through surface electromyography (sEMG)	From baseline to end of activity, up to 15 minutes	Muscle action potential amplitude (in millivolts - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.
Change from Baseline in perceived effort on the Borg category-ratio 10-point scale (CR 10)	From baseline to end of activity, up to 15 minutes	The perceived effort will be measured with Borg CR 10 scale. Possible scores range from 0 (no exertion at all) to 10 (extremely strong).
Change from Baseline in electrodermal activity (EDA)	From baseline to end of activity, up to 15 minutes	Electrical conductance (in microsiemens -µS) between two points of the hand over time measured before and during activity to track changes in autonomic function during activity.
Change from Baseline in heart rate	From baseline to end of activity, up to 15 minutes	Heart rate (heart beatings per minute) measured before and during activity to track cardiovascular changes during activity.
Change from Baseline in respiratory rate	From baseline to end of activity, up to 15 minutes	Respiratory rate (respiratory cycles per minute) measured before and during activity to track changes in respiratory function during activity.
Change from Baseline in muscle action potential duration through surface electromyography (sEMG)	From baseline to end of activity, up to 15 minutes	Muscle action potential duration (in milliseconds - ms) in surface electromyographic signal measured before and during activity to track muscular fatigue signs.
Change from Baseline in upper limb motion angular acceleration through inertial motion units (IMU) system	From baseline to end of activity, up to 15 minutes	Angular acceleration (in m/s\^2) of the arm measured before and during activity to track small movements of upper limb during isometric activity
Change from Baseline in muscle action potential frequency through surface electromyography (sEMG)	From baseline to end of activity, up to 15 minutes	Muscle action potential frequency (in hertz - Hz) of surface electromyographic signal measured before and during activity to track muscular fatigue signs.
Change from Baseline in respiratory pattern through inertial motion units (IMU) from baseline and during activity	From baseline to end of activity, up to 15 minutes	Angular range of motion (in degrees) of rib cage and abdominal wall during upper limb activity measured before and during activity to track changes in respiratory pattern during activity

Secondary Outcome Measures

Name	Time	Method
Health Status	Before isometric activity	Health Status will be measured with Medical Outcomes Study (MOS) Short Form Health Survey 36 Item version 2 which measure health status of populations and individuals. Possible scores range from 0 0 (worst health status) to 100 (best health status).
Physical activity level	Before isometric activity	Physical activity level will be measured using European Prospective Investigation into Cancer and Nutrition Physical Activity Questionnaire (EPIC-PAQ) that allows to estimate energy expenditure through self-report assessment of the intensity and average duration (per day, week and month) of physical activity performed by the participants in three distinct dimensions (professional, domestic and leisure).; Participants are classified as ACTIVE if they perform: at least 150 minutes per week of moderate physical activity; OR at least 75 minutes per week of vigorous physical activity; OR at least 150 minutes per week of a combination of moderate-intensity activity. If they don't present any of the conditions described, they will be categorized as SEDENTARY.

Trial Locations

Locations (1)

Escola Superior de Saúde da Cruz Vermelha Portuguesa - Lisboa; 🇵🇹 Lisboa, Portugal