Study to establish reference ranges for pregnancy for blood tests

Not Applicable

Completed

• Conditions: ooking at normal ranges in healthy pregnancy; Pregnancy and Childbirth

• Registration Number: ISRCTN17018939
• Lead Sponsor: Imperial College London

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2022-03-07
• Study Completion: 2023-02-01
• Last Update Posted: 1 April 2024

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 1200

Inclusion Criteria

1. Women over 18 years of age who are receiving antenatal care at Imperial College London NHS Trust
2. Singleton pregnancies

Exclusion Criteria

1. Multiple Pregnancies
2. Current or previous history of thyroid disease
3. Current or previous use of thyroid medications
4. Inability to understand and write in the English Language
5. Unable to participate for other factors as assessed by the Chief Investigators

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
evels of biochemical analytes in sampled blood will be analysed in accordance with national/international guidance:<br>1. Thyroid function - TSH, free T3, free T4<br>2. Thyroid peroxidase antibodies<br>3. Renin<br>4. Aldosterone<br>5. Folate<br>6. Iron<br>7. Troponin<br>8. Iodine

Secondary Outcome Measures

Name	Time	Method
Gestation of the pregnancy, the mother’s underlying health, and some demographic data measured at a single time point using a questionnaire