EMDR Treatment of Conditioned Nausea and Vomiting in Cancer Survivors - a Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 20
- 试验地点
- 1
- 主要终点
- Degree of conditioned nausea and vomiting
研究概览
简要总结
To explore the effectiveness of EMDR therapy treatment in reducing symptoms of chemotherapy-induced conditioned nausea and vomiting in (former) patients with cancer.
详细描述
Conditioned nausea and vomiting is a common side effect of anti-cancer treatment, and while strategies like antiemetics exist, their effectiveness is limited. Conditioned nausea and vomiting can possibly be addressed through Eye Movement Desensitization and Reprocessing (EMDR) therapy. EMDR therapy is a therapeutic intervention, proven to be effective in the treatment of post-traumatic stress disorder (PTSD), and promising in treating a range of other conditions. At the UMCG, EMDR therapy is used on a small scale to treat conditioned nausea with positive results, although more rigorous research is needed to fully establish its efficacy. This study aims to explore the effectiveness of EMDR therapy treatment in reducing symptoms of chemotherapy-induced conditioned nausea and vomiting in (former) patients with cancer.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 16 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Previously pathologically confirmed diagnosis of cancer
- •Previously treated with systemic cancer therapy
- •Persistent complaints (more than 2 months) of conditioned nausea and/or vomiting
- •Able to understand spoken and written Dutch
- •18 years or older
排除标准
- •Ongoing psychiatric treatment
- •EMDR therapy contraindications (dissociative disorders, personality disorders or severe somatic disorders (e.g. cardiac arrhythmias))
- •Complex type 2 trauma
- •Known with recent conditions / non-anti-cancer medication which can elicit nausea (e.g. pregnancy or alcohol abuses)
研究组 & 干预措施
EMDR Therapy
EMDR therapy sessions with a trained psychologist.
干预措施: EMDR therapy (Other)
结局指标
主要结局
Degree of conditioned nausea and vomiting
时间窗: Before intake EMDR therapy session and three weeks after last EMDR therapy session
Degree of conditioned nausea and vomiting after exposure to conditioned stimuli using the nausea profile questionnaire measured using the nausea profile questionnaire (9-point Likert scale, higher scores = worse outcome)
次要结局
- Impact on QoL of conditioned nausea and vomiting(Before EMDR therapy)