Management of Paroxystic Atrial Fibrillation in French Intensive Care Units
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 742
- 试验地点
- 14
- 主要终点
- Management of Atrial Fibrillation
研究概览
简要总结
The primary purpose of the study is to evaluate treatment of new onset atrial fibrillation in french ICU.
详细描述
Atrial fibrillation (AF) is a common arrhythmia in the ICU and is associated with significant morbidity. However, curative treatment remains unclearly established. In fact, there are no specific recommendations for new onset atrial fibrillation in ICU and only few studies have assessed this topic.
The PAF-ICU trial is an observational, prospective, multicenter, transversal trial. The main objective is to evaluate the management of paroxytic atrial fibrillation that occur in ICU.
The investigators want to document 2500 episodes of paroxystic atrial fibrillation in 50 ICU centers. In each center, the episodes are included consecutively until the required 50 episodes are obtained for each center.
A patient can present several episodes and each episode can be included in the study. A new episode is considered as such if it occurs more than one hour after the previous episode.
The follow-up period for each patient corresponds to the ICU stay.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age > 18 years
- •Patient hospitalized in ICU
- •New onset atrial fibrillation
排除标准
- •Age < 18 years
- •Parturient or breast-feeding woman
- •Persistent or permanent atrial fibrillation
- •Patients after cardiovascular or thoracic surgery
- •Patients with therapeutic limitations
结局指标
主要结局
Management of Atrial Fibrillation
时间窗: ICU stay (until 28 days)
All types of therapeutics used to manage atrial fibrillation are collected
次要结局
- Blood pressure(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)
- Vasopressors(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)
- Stroke(ICU Stay up to 28 days)
- Cardiac rhythm status(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)
- Heart rate(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)
- Cardiac output(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)
- ScvO2(Before, 5 minutes, 30 minutes, 1 hour, and 24 hours after atrial fibrillation)