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临床试验/NCT03743519
NCT03743519已完成不适用

The Efficacy of a Tart Cherry Drink for Patellofemoral Pain.

University of Central Lancashire2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2019年5月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
24
试验地点
2
主要终点
Knee injury and Osteoarthritis Outcome Score (KOOS) - patellofemoral scale

研究概览

简要总结

Patellofemoral pain (PFP) is the most common chronic pathology in sports medicine and physiotherapy clinics. As pain and inflammation are the main symptoms of PFP, non-steroidal anti-inflammatory and analgesic medications are often utilized to decrease pain and inflammation; however alternative treatments are increasingly being sought due to the cardiovascular and gastrointestinal side effects of traditional pain medications. Most researchers advocate conservative treatment, though there is still insufficient clarity regarding the effectiveness of conservative treatment modalities. Dietary interventions for PFP have not received any attention in clinical literature, yet there is a growing body of evidence indicating that cherries have significant anti-inflammatory, antioxidant and pain-mediating effects.

Therefore, the primary purpose of the proposed investigation was to test (using a randomized control investigation) the ability of a tart cherry juice blend to provide symptom relief in recreational athletes with PFP and to understand the biological and mechanical mechanisms behind any changes in PFP symptoms.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Treatment
盲法
Double (Participant, Investigator)

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Recreationally active
  • Suffering from mild to moderate patellofemoral pain with no evidence of any other condition.

排除标准

  • Rheumatoid arthritis or other systemic inflammatory condition
  • Chronic pain syndrome
  • Corticosteroid medication in last 2 months (intra-articular or oral)
  • Intra-articular injections of hyaluronic acid in the last 9 months
  • Pregnancy
  • Food allergies to cherries.

结局指标

主要结局

Knee injury and Osteoarthritis Outcome Score (KOOS) - patellofemoral scale

时间窗: 6-weeks

This is a questionnaire based measurement that allows participants to subjectively rate the extent of their patellofemoral pain symptoms. This measurement is scored on a 0-100 scale with 100 indicating no pain.

次要结局

  • Plasma urate(6-weeks)
  • human TNF-alpha(6-weeks)
  • Creatinine(6-weeks)
  • High sensitivity C-reactive protein(6-weeks)
  • COOP-WONCA - psychological wellbeing(6-weeks)
  • Pittsburgh Sleep Quality Index(6-weeks)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Jonathan Sinclair

Senior Lecturer

University of Central Lancashire

研究点 (2)

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