Role of Muscle Ultrasonography to assess Sarcopenia and its association with Frailty and short-term postoperative outcomes in oncosurgical patients - A Prospective Observational Study
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 86
- 试验地点
- 1
- 主要终点
- 1.Correlation coefficient of Muscle USG parameters with muscle strength (as assessed by hand-grip strength measured by dynamometer).
研究概览
简要总结
This is a Prospective Observational study to evaluate the role of Muscle ultrasonography in assessing Sarcopenia and its association with Frailty and short-term postoperative outcomes in oncosurgical patients. Muscle ultrasound will be used to measure both quantitative(muscle thickness) and qualitative (echogenic intensity) parameters, muscle strength will be measured with a hand grip dynamometer and gait speed( functional status) by four-meter walk test. All parameters will be measured one day before surgery. As Primary outcome we aim to measure the correlation of USG parameters with muscle strength and gait speed. As secondary outcome we also aim to study the association of the USG parameters with Frailty (assessed by FRAIL-Q, one day before surgery) and short-term postoperative outcome ( Clavien Dindo classification) until discharge of patient from hospital.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 50.00 Year(s) 至 85.00 Year(s)（—）
- 性别
- All
入选标准
- •Patients aged over 50 years of either sex undergoing elective oncological surgery under general anaesthesia.
排除标准
- •1.Neuromuscular diseases 2.Paresis 3.Paralysis or limb amputation 4.Dementia 5.Emergency surgery 6.Spinal cord injury 7.Obesity(male BMI≥35kg/m2,female BMI≥34.35kg/m2) 8.Acute heart failure, acute myocardial infarction, acute stroke.
结局指标
主要结局
1.Correlation coefficient of Muscle USG parameters with muscle strength (as assessed by hand-grip strength measured by dynamometer).
时间窗: One day before surgery. | Muscle USG, hand grip strength by dynamometer and gait speed (four meter walk test) will be performed on all patients one day before surgery.
2.Correlation coefficient of Muscle USG parameters with physical function status (as assessed by gait speed on four-meter walk test).
时间窗: One day before surgery. | Muscle USG, hand grip strength by dynamometer and gait speed (four meter walk test) will be performed on all patients one day before surgery.
次要结局
- 1.Correlation coefficient of USG parameters with frailty as assessed by Frail Q- Score(2.Association of measured sarcopenia with short-term postoperative outcomes (day of extubation, length of hospital & ICU stay, morbidity (Clavien-dindo scale), mortality until discharge).)
研究者
Dr Shivanya Singh
All India Institute of Medical Sciences, Bhopal