A multi-centre, randomised, double-blind, placebo controlled clinical trial examining the efficiency and safety of multi-vitamin therapy in secondary stroke preventio

Completed

• Conditions: Cardiovascular; Circulatory System; Stroke

• Registration Number: ISRCTN74743444
• Lead Sponsor: niversity of Glasgow and Greater Glasgow Health Board (UK)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2003-05-22
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: Not specified
• Target Recruitment: 8000

Inclusion Criteria

All patients presenting to one of the participating neurologists or general physicians within 7 months of stroke (ischaemic or haemorrhagic) or transient ischemic attack (TIA) (eye or brain) are eligible for this trial.

In addition the patient must:
1. Agree to take study medications
2. Be geographically accessible for follow up
3. Provide written informed consent

Exclusion Criteria

1. Taking folate or vitamin B6, on medical advice
2. Use of vitamin supplements containing B6, B12 or Folate (unless patient agrees to take study medication instead of the vitamin supplements which they usually take)
3. Taking Methotrexate for any reason
4. Pregnancy or women of child-bearing potential who are at risk of pregnancy
5. Limited life expectancy

Study & Design

• Study Type: Interventional
• Study Design: Not specified