CAD/CAM vs. conventional minimal invasive therapeutic intervention of severe non carious lesions: Clinical performance and quality of life improvement.

Not Applicable

• Conditions: K03.2; severe non-carious lesions; Erosion of teeth

• Registration Number: DRKS00010476
• Lead Sponsor: Heinrich-Heine-Universität Düsseldorf

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2018-04-03
• Study Completion: 2018-12-05
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting stopped after recruiting started
• Sex: All
• Target Recruitment: 2

Inclusion Criteria

Extensive erosive defects (BEWE Index 14-18 = necessity of a full-mouth rehabilitation; n = 14-28 teeth/patient) due to exogenous (acidic drinks) or endogenous factors (GERD or eating disorders), with severe loss of the vertical dimension of occlusion, hypersensitivity, reduced chewing ability, impaired aesthetics.

Exclusion Criteria

A history of alcohol or drug abuse, missing teeth, poor oral hygiene, pronounced parafunctions, with allergies to any of the applied materials or with life-threatening severe general diseases.

Study & Design

• Study Type: interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary endpoint is defined on an individual tooth-level as time from tooth restoration to failure, where failure is defined as the combined endpoint of restoration fracture, secondary caries, debonding, marginal discoloration, degradation of surface structure and anatomic form.

Secondary Outcome Measures

Name	Time	Method
Success 3 years after treatment.<br>Quality of dental restorations (USPHS criteria).<br>Patient’s centred satisfaction.<br>Safety.