Effect of calcium supplementation on iron bioavailability in women aged 35 to 45 years old

Not Applicable

Completed

• Conditions: Iron bioavailability, iron-calcium interaction; Nutritional, Metabolic, Endocrine; Iron deficiency

• Registration Number: ISRCTN89888123
• Lead Sponsor: niversity of Chile (Chile)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2011-07-13
• Last Update Posted: 3 July 2017

Recruitment & Eligibility

• Status: Completed
• Sex: Female
• Target Recruitment: 28

Inclusion Criteria

1. Apparently healthy women
2. Thirty five to 45 years old
3. Not participating in other clinical studies
4. Contraceptive use

Exclusion Criteria

1. Morbidity (excepting anemia defined as hemoglobin < 120 g/L)
2. Daily use of medicaments
3. Pregnancy and pregnant interest (including a pregnancy test before the start of the study)
4. Breastfeeding
5. Iron and/or calcium supplementation
6. Postmenopausal women
7. Participation in previous studies particularly involving the administration of radioactive labeled iron
8. Smoking

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Heme iron bioavailability <br>2. Non heme iron bioavailability

Secondary Outcome Measures

Name	Time	Method
1. Iron status<br>1.1. Hemoglobin<br>1.2. Mean corpuscular volume<br>1.3. Zn protoporphyrin<br>1.4. Serum ferritin<br>1.5. Total iron binding capacity<br>1.6. Serum Iron<br>1.7. Hepcidin<br>1.8. Transferrin Receptor<br>1.9. Transferrin Saturation<br>1.10. Total body iron<br>2. Nutritional state by anthropometry<br>3. Dietary calcium and iron daily intake